About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3690230
Allelic
Composition
Plaurtm1Jld/Plaurtm1Jld
Tg(MSR1-Plau)1Ddi/0
Genetic
Background
B6.Cg-Plaurtm1Jld Tg(MSR1-Plau)1Ddi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plaurtm1Jld mutation (2 available); any Plaur mutation (19 available)
Tg(MSR1-Plau)1Ddi mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• exhibit more fibrosis at 15 weeks of age than single Plaur homozygotes although show a similar degree of fibrosis as seen in single Tg(MSR1-Plau)1Ddi mutants
• exhibit significantly more cardiac macrophages at 15 weeks of age than single Plaur homozygotes, however show a similar accumulation as seen in single Tg(MSR1-Plau)1Ddi mutants

immune system
• exhibit significantly more cardiac macrophages at 15 weeks of age than single Plaur homozygotes, however show a similar accumulation as seen in single Tg(MSR1-Plau)1Ddi mutants


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/13/2026
MGI 6.24
The Jackson Laboratory