Phenotypes Associated with This Genotype

Genotype
MGI:3690222

• Allelic Composition: Tg(MSR1-Plau)1Ddi/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

enlarged heart ( J:101486 )

• hearts are more massive when fed the Western-type diet beginning at 5 weeks of age compared to controls, however do not develop atherosclerosis or show early mortality

cardiac fibrosis ( J:101486 )

• develop greater cardiac fibrosis than controls when fed a Western-type or normal chow diet

heart inflammation ( J:101486 )

• develop greater cardiac macrophage accumulation than controls when fed a Western-type or normal chow diet

immune system

heart inflammation ( J:101486 )

• develop greater cardiac macrophage accumulation than controls when fed a Western-type or normal chow diet

growth/size/body

enlarged heart ( J:101486 )

• hearts are more massive when fed the Western-type diet beginning at 5 weeks of age compared to controls, however do not develop atherosclerosis or show early mortality