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Phenotypes Associated with This Genotype
Genotype
MGI:3690099
Allelic
Composition		 Pax3Sp/Pax3+
Genetic
Background		 involves: C3HeB * C57BL * C57BL/6J * SWV
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pax3Sp mutation (4 available); any Pax3 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
spina bifida ( J:114747 )
• increased incidence of spina bifida induced by in utero exposure to 50 mg/kg trans-retinoic acid compared to treated wild-type littermates

embryo
spina bifida ( J:114747 )
• increased incidence of spina bifida induced by in utero exposure to 50 mg/kg trans-retinoic acid compared to treated wild-type littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory