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Phenotypes Associated with This Genotype
Genotype
MGI:3689354
Allelic
Composition
Tg(Ins2-Cxcl12)2Cys/0
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• only small and medium-sized infiltrates develop, and become prominent only at >4 months of age
• only small, occasional infiltrates develop in pancreatic islets, associated with HEVs and stromal cell networks; more frequent in older mice
• infiltrates consist primarily of naive T cells with few T cells and contain large proportions of DCs and plasma cells, in contrast to infiltrates in Ccl19 mice which have very few plasma cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory