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Phenotypes Associated with This Genotype
Genotype
MGI:3688524
Allelic
Composition		 Mc4rI194F/Mc4r+
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mc4rI194F mutation (0 available); any Mc4r mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:113730 )
• higher than wild-type
increased susceptibility to weight gain ( J:113730 )
• observed weight gain is significantly greater than wild-type between 5 and 20 weeks of age; males and females show similar weight gain to homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory