Phenotypes Associated with This Genotype

Genotype
MGI:3688523

• Allelic Composition: Mc4r^I194F/Mc4r^I194F
• Genetic Background: involves: C3HeB/FeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:113730 )

• mice display significantly higher body weight than wild-type littermates (females at week 11 are 138% of wild-type, at week 18 - 147%; males week 11- 116% at week 18, 123% of wild-type)

obese ( J:113730 )

increased susceptibility to weight gain ( J:113730 )

• observed weight gain is significantly greater than wild-type between 5 and 20 weeks of age; more pronounced in females than males