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Phenotypes Associated with This Genotype
Genotype
MGI:3687979
Allelic
Composition		 A/A
Mc1rE-tob/Mc1rE-tob
Genetic
Background		 M. m. domesticus poschiavinus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (80 available); any a mutation (468 available)
Mc1rE-tob mutation (4 available); any Mc1r mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:22593 )
• Mc1rE-tob influences the expression of agouti
darkened coat color ( J:22593 )
• the color is difficult to distinguish from non-agouti black before 8 weeks of age when agouti hairs appear on the flanks; the back remains darkened
• Mc1rE-tob/Mc1re mice that are also homozygous non-agouti are black because Mc1rE-tob only affects the expression of agouti

integument
abnormal coat/hair pigmentation ( J:22593 )
• Mc1rE-tob influences the expression of agouti
darkened coat color ( J:22593 )
• the color is difficult to distinguish from non-agouti black before 8 weeks of age when agouti hairs appear on the flanks; the back remains darkened
• Mc1rE-tob/Mc1re mice that are also homozygous non-agouti are black because Mc1rE-tob only affects the expression of agouti

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory