Phenotypes Associated with This Genotype

Genotype
MGI:3665462

• Allelic Composition: Dcc^kanga/Dcc^tm1Wbg
• Genetic Background: involves: 129X1/SvJ * AKR * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

ataxia ( J:80430 )

nervous system

abnormal axon guidance ( J:80430 )

• axons fail to cross the midline at the pyramidal decussation and instead extend into the lateral and ventral funiculus

absent corpus callosum ( J:80430 )

absent hippocampal commissure ( J:80430 )

• absent hippocampal commissure

abnormal pyramidal decussation morphology ( J:80430 )

• no axons cross the midline at the pyramidal decussation

abnormal corticospinal tract morphology ( J:80430 )

• absent from the dorsal funiculus

cellular

abnormal axon guidance ( J:80430 )

• axons fail to cross the midline at the pyramidal decussation and instead extend into the lateral and ventral funiculus