About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3664570
Allelic
Composition		 Lrp5tm1Lex/Lrp5tm1Lex
Genetic
Background		 involves: 129/Sv * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5tm1Lex mutation (0 available); any Lrp5 mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
decreased bone mineral density ( J:111359 )
• homozygotes have lower bone mineral density (BMD) than wild-type or heterozygous littermates; differences become significant at 29 days of age and persists thereafter

vision/eye
persistence of hyaloid vascular system ( J:111359 )
• mutants display this abnormality in eye vascularization

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory