Phenotypes Associated with This Genotype

Genotype
MGI:3663940

• Allelic Composition: Lhx1^tm1Bhr/Lhx1⁺; Ssbp3^{Tg(SOD1)1Hssk}/Ssbp3⁺
• Genetic Background: involves: 129S7/SvEvBrd * C3H/He * C57BL/6 * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

embryonic growth retardation ( J:98485 )

• some double heterozygotes display severe growth retardation and microcephaly

microcephaly ( J:98485 )

• double heterozygotes display variable degrees of microcephaly; some embryos appear normal, others display microcephaly while another subset show microcephaly and severe growth retardation

embryo

failure of initiation of embryo turning ( J:98485 )

• the most severely affected double heterozygotes fail to undergo embryonic turning

embryonic growth retardation ( J:98485 )

• some double heterozygotes display severe growth retardation and microcephaly