Mouse Genome Informatics
tg
    Tg(APP695)3Dbo/0
involves: C3H/HeJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
N
• no immunoreactive amyloid beta deposits found in cortex or hippocampus from 12 month old mice as compared to double transgenic mice: Tg(APP695)3Dbo/0, Tg(PSEN1)5Dbo/0 (J:43788)
• amyloid beta deposits observed in cortex and hippocampus of 18 and 20 month old mice (J:43788)
• ratio of amyloid beta peptide 40:42 is 3:1 (J:87691)

other phenotype
• amyloid beta deposits observed in cortex and hippocampus of 18 and 20 month old mice (J:43788)
• ratio of amyloid beta peptide 40:42 is 3:1 (J:87691)

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:87691