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Phenotypes Associated with This Genotype
Genotype
MGI:3663374
Allelic
Composition		 Smn1tm1Hung/Smn1tm1Hung
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smn1tm1Hung mutation (4 available); any Smn1 mutation (87 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:59313 )
• homozygous blastocysts appeared normal at E3.5, but could not be identified after E6.5
• in culture, homozygous blastocysts did not attach during the first 1-2 days and exhibited extensive cellular degeneration during the first 12-36 hours

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory