Phenotypes Associated with This Genotype

Genotype
MGI:3663263

• Allelic Composition: Otx2^tm1Sla/Otx2⁺
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:30828 )

• slightly lower numbers of heterozygotes are obtained at 3 weeks of age than expected

nervous system

open neural tube ( J:30828 )

• open at the forebrain and midbrain levels

embryo

open neural tube ( J:30828 )

• open at the forebrain and midbrain levels