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Phenotypes Associated with This Genotype
Genotype
MGI:3663041
Allelic
Composition
Tg(Ins2-Fas*I246N)1Ach/0
Tg(Ins2-Fasl)24Ach/0
Genetic
Background
NOD-Tg(Ins2-Fas*I246N)1Ach Tg(Ins2-Fasl)24Ach
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ins2-Fas*I246N)1Ach mutation (1 available)
Tg(Ins2-Fasl)24Ach mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• double transgenics show slower onset of diabetes compared to NOD-Tg(Ins2-Fasl)24Ach single transgenics

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
J:81416


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory