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Phenotypes Associated with This Genotype
Genotype
MGI:3662883
Allelic
Composition
Glra2tm1Clc/Glra2tm1Clc
Genetic
Background
involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glra2tm1Clc mutation (1 available); any Glra2 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• E17 cortical pyramidal neurons fail to respond to glycine or taurine in single cell patch clamp assays
• however, these cells respond normally to GABA and cortex morphology at P0 and in adults is indistinguishable from wild-type

vision/eye
N
• retinal morphology is similar to wild-type and no differences in electroreinograms are detected

reproductive system
N
• fertile with normal breeding behavior

behavior/neurological
N
• normal gait and feeding behavior


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory