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Phenotypes Associated with This Genotype
Genotype
MGI:3662664
Allelic
Composition		 Tg(Igh-6-Cd80)1Gjf/0
Genetic
Background		 B6.Cg-Tg(Igh-6-Cd80)1Gjf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Igh-6-Cd80)1Gjf mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:112266 )
N
• there is no significant difference in lymphoid organ cellularity compare to Cd86 transgenic mice
abnormal T cell number ( J:112266 )
• CD4/CD8 ratios in the thymus and spleen are significantly lower than those of control littermates

immune system
abnormal T cell number ( J:112266 )
• CD4/CD8 ratios in the thymus and spleen are significantly lower than those of control littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory