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Phenotypes Associated with This Genotype
Genotype
MGI:3662644
Allelic
Composition		 B2mtm1Jae/B2mtm1Jae
Tg(H2-K-Cd86)27All/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B2mtm1Jae mutation (8 available); any B2m mutation (117 available)
Tg(H2-K-Cd86)27All mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
absent B cells ( J:112475 )
• no B cells are detected in blood of B2m-deficient transgenic mice

immune system
absent B cells ( J:112475 )
• no B cells are detected in blood of B2m-deficient transgenic mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory