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Phenotypes Associated with This Genotype
Genotype
MGI:3656135
Allelic
Composition		 Cyp1a2tm1Dwn/Cyp1a2tm1Dwn
Genetic
Background		 either: (involves: 129P2/OlaHsd * Black Swiss) or (involves: 129P2/OlaHsd * CF-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyp1a2tm1Dwn mutation (1 available); any Cyp1a2 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
enhanced behavioral response to xenobiotic ( J:31730 )
• remain paralyzed at least 9 times longer than wild-type mice after treatment with zoxazolamine and no difference in the length of paralysis is seen with or without beta-naphthoflavone pretreatment
• in the absence of treatment no morphological or developmental abnormalities are detected

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory