Mouse Genome Informatics
hm
    Cyp1b1tm1Gonz/Cyp1b1tm1Gonz
involves: 129X1/SvJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
vision/eye
• angle abnormalities are present focally, detectable only by historical and electron microscopic analyses
• no gross abnormality observed
• intraocular pressure is indistinguishable from that of normal littermates
• in this mixed background, albino homozygous mice show more severe angle defects than pigmented homozygous mice
• a small or absent Schlemm's canal
• basal lamina extends from the cornea over the trabecular meshwork
• attachments of the iris to the trabecular meshwork and peripheral cornea

Mouse Models of Human Disease
OMIM IDRef(s)
Glaucoma 3, Primary Congenital, A; GLC3A 231300 J:82280