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Phenotypes Associated with This Genotype
Genotype
MGI:3655810
Allelic
Composition		 Aqp3tm1Ask/Aqp3tm1Ask
Genetic
Background		 involves: C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp3tm1Ask mutation (0 available); any Aqp3 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:71154 )
N
• auditory brainstem response thresholds are similar to wild-type

vision/eye
vision/eye phenotype ( J:62579 )
N
• basal and pilocarpine-stimulated tear production and chloride concentration are similar to wild-type

taste/olfaction
abnormal olfactory epithelium morphology ( J:106285 )
• osmotic water permeability is inhibited by 35% compared to wild-type

respiratory system
abnormal olfactory epithelium morphology ( J:106285 )
• osmotic water permeability is inhibited by 35% compared to wild-type

craniofacial
abnormal olfactory epithelium morphology ( J:106285 )
• osmotic water permeability is inhibited by 35% compared to wild-type

growth/size/body
abnormal olfactory epithelium morphology ( J:106285 )
• osmotic water permeability is inhibited by 35% compared to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory