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Phenotypes Associated with This Genotype
Genotype
MGI:3653430
Allelic
Composition
Tubtub/Tubtub
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tubtub mutation (3 available); any Tub mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• defect in neuronal ciliary localization of SSTR3 and MCHR1 in the hippocampus CA1 region
• absence of NPY2R in arcuate nucleus cilia; however, overall NPY2R expression levels in the hypothalamus are similar to controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory