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Phenotypes Associated with This Genotype
Genotype
MGI:3653041
Allelic
Composition
Tg(Mt1-Tnfsf4)2Pgn/?
Genetic
Background
C57BL/6J-Tg(Mt1-Tnfsf4)2Pgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Mt1-Tnfsf4)2Pgn mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• sizes of atherosclerotic lesions at the aortic roots of transgenic female mice were ~2.3-fold greater than those of their nontransgenic littermates after 16 weeks on an atherogenic diet begun at age 10 weeks

homeostasis/metabolism
N
• plasma levels of triglycerides, total cholesterol, VLDL cholesterol and HDL cholesterol were similar for transgenic females and their non-transgenic littermates both before and after 16 weeks on a high fat diet begun at age 10 weeks


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory