About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3652977
Allelic
Composition		 Cd40lgtm1Imx/Cd40lgtm1Imx
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Imx mutation (4 available); any Cd40lg mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell clonal deletion ( J:110925 )
• mice show complete rescue of CD8+ and CD4+ V beta11+ and beta6+ bearing CD4+ and CD8+ thymocytes from deletion in the thymus and periphery and Vbeta5+ CD4+ cells, but not Vbeta5+ bearing CD8+ thymocytes

hematopoietic system
abnormal T cell clonal deletion ( J:110925 )
• mice show complete rescue of CD8+ and CD4+ V beta11+ and beta6+ bearing CD4+ and CD8+ thymocytes from deletion in the thymus and periphery and Vbeta5+ CD4+ cells, but not Vbeta5+ bearing CD8+ thymocytes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory