About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3652975
Allelic
Composition		 Cd28tm1Mak/Cd28tm1Mak
Cd5tm1Cgn/Cd5+
Genetic
Background		 either: (involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA/1 * LP)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd28tm1Mak mutation (13 available); any Cd28 mutation (37 available)
Cd5tm1Cgn mutation (1 available); any Cd5 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell clonal deletion ( J:110925 )
• mice show partial rescue of Vbeta11+CD4+ thymocytes from negative selection

hematopoietic system
abnormal T cell clonal deletion ( J:110925 )
• mice show partial rescue of Vbeta11+CD4+ thymocytes from negative selection

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory