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Phenotypes Associated with This Genotype
Genotype
MGI:3652806
Allelic
Composition		 Gba1tm1Bst/Gba1tm1Nsb
Gba/Mtx1tm1Bst/Mtx1+
Genetic
Background		 involves: 129S/SvEv * 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gba1tm1Bst mutation (0 available); any Gba1 mutation (47 available)
Gba1tm1Nsb mutation (2 available); any Gba1 mutation (47 available)
Gba/Mtx1tm1Bst mutation (0 available); any Mtx1 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:25197 )
• animals die within 24 hours of birth

homeostasis/metabolism
abnormal enzyme/coenzyme activity ( J:25197 )
• mutants have about 5% of control glucocerebrosidase enzyme activity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory