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Phenotypes Associated with This Genotype
Genotype
MGI:3641207
Allelic
Composition		 Sox5tm1Vlf/Sox5tm1Vlf
Sox6tm1Vlf/Sox6tm2.1Vlf
Tg(Col2a1-cre)1Bhr/0
Genetic
Background		 involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox5tm1Vlf mutation (0 available); any Sox5 mutation (44 available)
Sox6tm1Vlf mutation (0 available); any Sox6 mutation (56 available)
Sox6tm2.1Vlf mutation (0 available); any Sox6 mutation (56 available)
Tg(Col2a1-cre)1Bhr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal cartilage development ( J:110147 )
• poorly developed cartilage similar to double homozygous mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory