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Phenotypes Associated with This Genotype
Genotype
MGI:3639578
Allelic
Composition		 Itgb1tm1.1Efu/Itgb1tm1.1Efu
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm1.1Efu mutation (0 available); any Itgb1 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:108331 )
• at E6.5, homozygous embryos are resorbed, with only a residual population of trophoblast cells visible

embryo
absent inner cell mass ( J:108331 )
• at E6.5, embryos fail to develop an inner cell mass: embryos are identified by presence of persistent trophoblastic cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory