Phenotypes for Snx1 Snx2 Vps26a MGI:3639310 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Snx1^tm1Mag/Snx1⁺ Snx2^tm1Mag/Snx2^tm1Mag Vps26a^tm1Cos/Vps26a⁺
Genetic Background	involves: 129S/SvEv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snx1^tm1Mag mutation (1 available); any Snx1 mutation (22 available)
Snx2^tm1Mag mutation (1 available); any Snx2 mutation (41 available)
Vps26a^tm1Cos mutation (1 available); any Vps26a mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:102476 )

• second wave of lethality is around E13.5

embryonic lethality between somite formation and embryo turning, incomplete penetrance ( J:102476 )

• first wave of lethality is around E8.5

prenatal lethality, complete penetrance ( J:102476 )

• 100% die during development

growth/size/body

embryonic growth retardation ( J:102476 )

• embryos that die by E8.5 are underdeveloped and undergo developmental delay beginning at E7.5

nervous system

exencephaly ( J:102476 )

• embryos that die around E13.5, exhibit exencephaly

embryo

embryonic growth retardation ( J:102476 )

• embryos that die by E8.5 are underdeveloped and undergo developmental delay beginning at E7.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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