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Phenotypes Associated with This Genotype
Genotype
MGI:3639277
Allelic
Composition		 Gata4tm1.1Wtp/Gata4tm1.1Wtp
Tg(Myh6-cre)2182Mds/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata4tm1.1Wtp mutation (0 available); any Gata4 mutation (37 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
heart hypoplasia ( J:99203 )
• marked myocardial hyperplasia
decreased fetal cardiomyocyte proliferation ( J:99203 )
• reduction in cardiomyocyte proliferation

muscle
decreased fetal cardiomyocyte proliferation ( J:99203 )
• reduction in cardiomyocyte proliferation

cellular
decreased fetal cardiomyocyte proliferation ( J:99203 )
• reduction in cardiomyocyte proliferation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory