Phenotypes Associated with This Genotype

Genotype
MGI:3639139

• Allelic Composition: Tg(Myh6-Akt1)564Anr/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal myocardial fiber morphology ( J:77257 )

• myocytes are larger with a 1.7-fold greater mean surface area

cardiac hypertrophy ( J:77257 )

• the heart weight/body weight ratio is 2.5- and 2.1-fold greater than in wild-type female and male littermates

muscle

abnormal myocardial fiber morphology ( J:77257 )

• myocytes are larger with a 1.7-fold greater mean surface area

growth/size/body

cardiac hypertrophy ( J:77257 )

• the heart weight/body weight ratio is 2.5- and 2.1-fold greater than in wild-type female and male littermates