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Phenotypes Associated with This Genotype
Genotype
MGI:3628914
Allelic
Composition
Dnmt3btm1Enl/Dnmt3btm6Enl
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnmt3btm1Enl mutation (1 available); any Dnmt3b mutation (29 available)
Dnmt3btm6Enl mutation (0 available); any Dnmt3b mutation (29 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• normal numbers of pups are born but most die within 24 hours

immune system
• at P1, many thymocytes are dead or dying

growth/size/body
• at birth, mutants are less than 2/3 the weight of normal littermates

hematopoietic system
• at P1, many thymocytes are dead or dying

cellular
• at P1, many thymocytes are dead or dying

endocrine/exocrine glands
• at P1, many thymocytes are dead or dying


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory