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Phenotypes Associated with This Genotype
Genotype
MGI:3625926
Allelic
Composition		 Sox2tm1Lpev/Sox2tm2Lpev
Tg(Pax6-cre,GFP)2Pgr/?
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox2tm1Lpev mutation (1 available); any Sox2 mutation (55 available)
Sox2tm2Lpev mutation (1 available); any Sox2 mutation (55 available)
Tg(Pax6-cre,GFP)2Pgr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal eye size ( J:108452 )
• a further reduction in eye size at E14.5 compared to Sox2tm1Lpev/Sox2tm3Lpev or Sox2tm1Lpev/Sox2tm4Lpev hypomorphs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory