Analysis Tools
immune system
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• in the thymus of transgenic male Hcls1-null mice, significant numbers of double positive thymocytes do not undergo negative selection and remain undeleted
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• in Hcls1-expressing transgenic male mice, the population of double positive thymocytes is reduced to 10% of that in female ransgenic Hcls1-expressing animals
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hematopoietic system
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• in the thymus of transgenic male Hcls1-null mice, significant numbers of double positive thymocytes do not undergo negative selection and remain undeleted
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• in Hcls1-expressing transgenic male mice, the population of double positive thymocytes is reduced to 10% of that in female ransgenic Hcls1-expressing animals
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