Analysis Tools
hematopoietic system
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• purified T cells from null mice display reduced proliferation in culture compared to wild-type cells in response to anti-CD3, but proliferation of T cells is not reduced to same extent as proliferation of B cells in mutants
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• in null mice, multivalent crosslinking of B cell surface antigen receptors does not significantly decrease the number of peritoneal B cells, as is seen in control mice
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• in null mice, multivalent crosslinking of B cell surface antigen receptors does not significantly decrease the number of peritoneal B cells, as is seen in control mice
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immune system
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• purified T cells from null mice display reduced proliferation in culture compared to wild-type cells in response to anti-CD3, but proliferation of T cells is not reduced to same extent as proliferation of B cells in mutants
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• in null mice, multivalent crosslinking of B cell surface antigen receptors does not significantly decrease the number of peritoneal B cells, as is seen in control mice
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• in null mice, multivalent crosslinking of B cell surface antigen receptors does not significantly decrease the number of peritoneal B cells, as is seen in control mice
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• antibody production to type II T-independent antigens is reduced in null mice while production of T-dependent antigen antibodies is not compared with levels in controls
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cellular
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• purified T cells from null mice display reduced proliferation in culture compared to wild-type cells in response to anti-CD3, but proliferation of T cells is not reduced to same extent as proliferation of B cells in mutants
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