Phenotypes Associated with This Genotype

Genotype
MGI:3625117

• Allelic Composition: Tg(Scgb1a1-Has2)1Nbl/0
• Genetic Background: C57BL/6J-Tg(Scgb1a1-Has2)1Nbl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:102879 )

• when transgenic mice are challenged with high doses of bleomycin, they show improved survival relative to non-transgenic controls

cellular

decreased apoptosis ( J:102879 )

• transgenic mice display less lung epithelial apoptotis 5 days after injury compared to controls

homeostasis/metabolism

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:102879 )

• when transgenic mice are challenged with high doses of bleomycin, they show improved survival relative to non-transgenic controls