Mouse Genome Informatics
hm
    Il4tm1Cgn/Il4tm1Cgn
either: NOD.129-Il4tm1Cgn or (involves: 129 * NOD)
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
endocrine/exocrine glands
• at 12 weeks, insulitis incidence is similar in homozygous mutants and heterozygous controls on the NOD background (N4)

immune system
• at 12 weeks, insulitis incidence is similar in homozygous mutants and heterozygous controls on the NOD background (N4)
• there is no difference in timing or penetrance of diabetes in IL4-deficient NOD mice (N8) compared to heterozygous or wild-type NOD mice

Mouse Models of Human Disease
OMIM IDRef(s)
Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:85924