Phenotypes for Mbd2 Mecp2 MGI:3624722 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mbd2^tm1Bh/Mbd2^tm1Bh Mecp2^tm1.1Bird/Y
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mbd2^tm1Bh mutation (1 available); any Mbd2 mutation (21 available)
Mecp2^tm1.1Bird mutation (1 available); any Mecp2 mutation (38 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:67910 )

• exhibit the same mortality as single homozygous Mecp2 null mice

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:67910 )

• exhibit the same onset of Rett-like syndrome symptoms and mortality as single homozygous Mecp2 null mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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