Mouse Genome Informatics
ht
    Mecp2tm1.1Bird/Mecp2+
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• acquire hindlimb clasping at ages greater than 3 months
• although heterozygous females initially show no symptoms and raise normal litters, they acquire inertia at ages greater than 3 months
• in an open field test, visit fewer squares, spend more time being immotile and rear less than controls, however this is not due to increased anxiety, as fecal bolus counts, grooming times and time spent in different zones of the field are similar to controls

respiratory system
• often exhibit breathing irregularities by 9 months of age

Mouse Models of Human Disease
OMIM IDRef(s)
Rett Syndrome; RTT 312750 J:67910