Phenotypes for Dync2h1 MGI:3624273 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dync2h1^{Gt(RRM278)Byg}/Dync2h1^lln
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dync2h1^{Gt(RRM278)Byg} mutation (0 available); any Dync2h1 mutation (215 available)
Dync2h1^lln mutation (0 available); any Dync2h1 mutation (215 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:100466 )

• mutants die around E12.5

cardiovascular system

abnormal direction of heart looping ( J:100466 )

• mutants exhibit randomization of heart looping polarity

nervous system

abnormal brain morphology ( J:100466 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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