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Phenotypes Associated with This Genotype
Genotype
MGI:3623731
Allelic
Composition
Tpm1tm1Dfw/Tpm1+
Genetic
Background
involves: 129P2/OlaHsd * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tpm1tm1Dfw mutation (0 available); any Tpm1 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• heterozygotes are viable and fertile and exhibit no abnormalities in cardiac morphology or myocardial function, as shown by normal heart rates, intraventricular pressures, and rates of contraction and relaxation as well as normal Ca2+ activation of myofilaments in skinned fiber bundles


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory