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Phenotypes Associated with This Genotype
Genotype
MGI:3623591
Allelic
Composition
Tg(Igh-6/Igh-V281)3Jwt/0
Genetic
Background
NOD.B6-Tg(Igh-6/Igh-V281)3Jwt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Igh-6/Igh-V281)3Jwt mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• by 40 weeks, pancreata of transgenic mice show extensive infiltrates

immune system
• by 40 weeks, pancreata of transgenic mice show extensive infiltrates
• transgenic mice are protected from developing diabetes; 16% develop diabetes by 40 weeks

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
J:91865


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory