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Phenotypes Associated with This Genotype
Genotype
MGI:3623128
Allelic
Composition		 Drd2tm1Schm/Drd2+
Drd3tm1Schm/Drd3tm1Schm
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drd2tm1Schm mutation (0 available); any Drd2 mutation (70 available)
Drd3tm1Schm mutation (0 available); any Drd3 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal locomotor behavior ( J:79483 )
• male mice 70 days old show decreased locomotor activity and distance traveled compared to wild-type but these parameters are still significantly greater than double homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory