Mouse Genome Informatics
cx
    Prf1tm1Clrk/Prf1tm1Clrk
Tg(INS-Il10)#Sar/0

involves: 129S7/SvEvBrd * BALB/c * NOD
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
immune system
• only 11% of animals develop diabetes by 5 weeks of age (blood glucose >300 mg/dl), while 50% of wild-type transgenic animals develop diabetes, but the overall incidence by 12 weeks is the same for both
• mice are considered diabetic after a blood glucose measure of >300 mg/dl

Mouse Models of Human Disease
OMIM IDRef(s)
Diabetes Mellitus, Insulin-Dependent; IDDM 222100 J:64051