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Phenotypes Associated with This Genotype
Genotype
MGI:3622539
Allelic
Composition		 Pecam1tm1Mak/Pecam1+
Genetic
Background		 D1.129P2-Pecam1tm1Mak
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pecam1tm1Mak mutation (1 available); any Pecam1 mutation (227 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to induced arthritis ( J:106275 )
• susceptibility to induced arthritis MP:0003724heterozygotes display an intermediate incidence of arthritis compared to nulls and wild-type mice

skeleton
increased susceptibility to induced arthritis ( J:106275 )
• susceptibility to induced arthritis MP:0003724heterozygotes display an intermediate incidence of arthritis compared to nulls and wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory