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Phenotypes Associated with This Genotype
Genotype
MGI:3622192
Allelic
Composition		 GnasOedsml/Gnas+
Gnasas1tm1Jop/Gnasas1+
Genetic
Background		 involves: 101/H * 129S/SvEv * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnasas1tm1Jop mutation (0 available); any Gnasas1 mutation (6 available)
GnasOedsml mutation (0 available); any Gnas mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
edema ( J:106793 )
• when Nepastm1Jop is paternally inherited and GnasOedsml-mat is maternally inherited the incidence of edema is reduced (6 of 32 develop edema) compared to mice heterozygous for GnasOedsml-mat alone (20 of 20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory