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Phenotypes Associated with This Genotype
Genotype
MGI:3622124
Allelic
Composition		 Abcb1atm1Bor/Abcb1atm1Bor
Abcb1btm1Bor/Abcb1btm1Bor
Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic
Background		 FVB.129P2-Abcb1btm1Bor Abcb1atm1Bor Abcc2tm1Ahs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcb1atm1Bor mutation (3 available); any Abcb1a mutation (93 available)
Abcb1btm1Bor mutation (2 available); any Abcb1b mutation (82 available)
Abcc2tm1Ahs mutation (0 available); any Abcc2 mutation (90 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal xenobiotic pharmacokinetics ( J:107822 )
• bilary excretion of doxorubicin is reduced to about 2% normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory