Analysis Tools
immune system
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• mean insulitis scores increased over controls at 18 weeks of age but not at 10 weeks
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• reduced production of PGE2 and increased TNF alpha production by stimulated peritoneal macrophage at 18 weeks of age
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homeostasis/metabolism
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• increased incidence of diabetes
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endocrine/exocrine glands
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• mean insulitis scores increased over controls at 18 weeks of age but not at 10 weeks
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hematopoietic system
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• reduced production of PGE2 and increased TNF alpha production by stimulated peritoneal macrophage at 18 weeks of age
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