Phenotypes Associated with This Genotype

Genotype
MGI:3621457

• Allelic Composition: Maml1^tm1Lizw/Maml1^tm1Lizw
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:106711 )

• die within 10 days of birth

growth/size/body

decreased body size ( J:106711 )

• remain smaller after birth

fetal growth retardation ( J:106711 )

• delayed growth visible at birth

muscle

skeletal muscle fiber necrosis ( J:106711 )

• degeneration and necrosis of some but not all myofibers

increased variability of skeletal muscle fiber size ( J:106711 )

• variable myofiber size (atrophic and hypertrophic)

cellular

skeletal muscle fiber necrosis ( J:106711 )

• degeneration and necrosis of some but not all myofibers