Phenotypes Associated with This Genotype

Genotype
MGI:3620213

• Allelic Composition: Tcrd^tm1Mom/Tcrd^tm1Mom
• Genetic Background: FVB.129P2-Tcrd^tm1Mom

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to type IV hypersensitivity reaction ( J:75915 )

• Background Sensitivity: aggravated allergic contact dermatitis in response to DNFAB and irritant contact dermatitis

dermatitis ( J:75915 )

• Background Sensitivity: no overt signs of spontaneous dermatitis on this background

homeostasis/metabolism

impaired skin barrier function ( J:106782 )

• transepidermal water loss as measured by skin surface impedance is increased under environmentally stressful conditions

integument

impaired skin barrier function ( J:106782 )

• transepidermal water loss as measured by skin surface impedance is increased under environmentally stressful conditions

dermatitis ( J:75915 )

• Background Sensitivity: no overt signs of spontaneous dermatitis on this background

abnormal skin condition ( J:75915 )

• Background Sensitivity: less extensive ear thickening