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Phenotypes Associated with This Genotype
Genotype
MGI:3620122
Allelic
Composition		 Stat4tm1Gru/Stat4tm1Gru
Tg(Ins2-GP)34-20Olds/0
Genetic
Background		 involves: 129S2/SvPas * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat4tm1Gru mutation (4 available); any Stat4 mutation (64 available)
Tg(Ins2-GP)34-20Olds mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal susceptibility to autoimmune disorder ( J:107047 )
• Stat4 deficiency does not affect the incidence of CD4+ T cell independent diabetes

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
type 1 diabetes mellitus DOID:9744 OMIM:222100
 J:107047

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory